Sex differences in the association between body mass index and hypertension - a cross-sectional study in 717 812 adolescents

Pediatr Obes. 2016 Aug;11(4):317-20. doi: 10.1111/ijpo.12029. Epub 2015 Apr 27.

Abstract

In order to examine sex-specific differences in the association of body mass index (BMI) and hypertension, we conducted a retrospective, cross-sectional study of 717 812 (402 914 men and 314 898 women) Israeli Jewish adolescents aged 16.0-19.99 years medically screened for military service. A diagnosis of hypertension was established per history or if a mean of 10 separate blood pressure measurements exceeded 140/90, following an initial measurement higher than 140/90. Weight and height were measured. Prevalence of hypertension was 0.42% in men and 0.05% in women. In men, BMI was significantly associated with hypertension from the third decile (odds ratio [OR] 1.67, 1.06-2.65) up to the 10th decile (OR 30.17, 20.83-43.69). In women, we observed a significantly increased risk for hypertension in the ninth decile (OR 3.82, 1.42-10.22) and in the 10th decile (OR 18.92, 7.7-46.51), with no visible trend in lower deciles. BMI effects on hypertension prevalence are different in male and female adolescents.

Keywords: Adolescents; body mass index; hypertension; sex.

MeSH terms

  • Adolescent
  • Blood Pressure / physiology
  • Body Mass Index*
  • Body Weight
  • Cross-Sectional Studies
  • Female
  • Humans
  • Hypertension / epidemiology*
  • Israel
  • Male
  • Prevalence
  • Retrospective Studies
  • Risk Factors
  • Sex Factors*
  • Young Adult