Localized lymph node light chain amyloidosis

Binod Dhakal; Alexandra M Harrington; Michael E Stadler; Anita D'Souza

doi:10.1155/2015/816565

Localized lymph node light chain amyloidosis

Case Rep Hematol. 2015:2015:816565. doi: 10.1155/2015/816565. Epub 2015 Apr 2.

Authors

Binod Dhakal¹, Alexandra M Harrington², Michael E Stadler³, Anita D'Souza¹

Affiliations

¹ Division of Hematology & Oncology, Medical College of Wisconsin, 9200 W. Wisconsin Avenue, Milwaukee, WI 53226, USA.
² Department of Pathology, Medical College of Wisconsin, 9200 W. Wisconsin Avenue, Milwaukee, WI 53226, USA.
³ Department of Otolaryngology and Communication Sciences, Medical College of Wisconsin, 9200 W. Wisconsin Avenue, Milwaukee, WI 53226, USA.

Abstract

Immunoglobulin-derived light chain amyloidosis can occasionally be associated with localized disease. We present a patient with localized lymph node light chain amyloidosis without an underlying monoclonal protein or lymphoproliferative disorder and review the literature of lymph node amyloidosis discussing work-up and risk factors for systemic progression.