There are many prognostic factors in neuroblastoma. In this paper we analyzed the prognostic importance of some clinical factors like age, stage of disease, primary localization and neurological manifestations in children with neuroblastoma. We analyzed 58 children with neuroblastoma who were treated from 1970 to 1988 at the Haematology Department of Children's University Hospital in Belgrade. According to statistical evaluation presence of neurological manifestations and age were not important prognostic factors in children with neuroblastoma. Only primary localization of the tumour and stage of the disease had significant influence on prognosis.