Intracranial involvement by multiple myeloma

A Lasocki; S Gangatharan; F Gaillard; S J Harrison

doi:10.1016/j.crad.2015.03.014

Intracranial involvement by multiple myeloma

Clin Radiol. 2015 Aug;70(8):890-7. doi: 10.1016/j.crad.2015.03.014. Epub 2015 May 5.

Authors

A Lasocki¹, S Gangatharan², F Gaillard³, S J Harrison⁴

Affiliations

¹ Department of Cancer Imaging, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia; Department of Diagnostic Imaging, Monash Health, Clayton, Victoria, Australia. Electronic address: [email protected].
² Department of Haematology, Fremantle Hospital, Fremantle, Western Australia, Australia.
³ Department of Radiology, The Royal Melbourne Hospital, Parkville, Victoria, Australia; Department of Radiology, The University of Melbourne, Parkville, Victoria, Australia.
⁴ Department of Cancer Medicine, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia.

PMID: 25956664
DOI: 10.1016/j.crad.2015.03.014

Abstract

Intracranial involvement is a rare complication of multiple myeloma. It results either from direct extra-osseous spread from adjacent skeletal plasmacytomas or extra-medullary disease via haematogenous dissemination. The imaging appearances are non-specific, and dural, leptomeningeal, and parenchymal involvement can all occur. The purpose of this review is to illustrate the various neuroimaging appearances of this rare entity, focusing on MRI.

Publication types

Review

MeSH terms

Brain Neoplasms / diagnosis*
Brain Neoplasms / secondary
Humans
Magnetic Resonance Imaging / methods*
Multiple Myeloma / diagnosis*
Multiple Myeloma / secondary