Shedding light on glioma growth

Emily K Lehrman; Beth Stevens

doi:10.1016/j.cell.2015.04.036

Shedding light on glioma growth

Cell. 2015 May 7;161(4):704-6. doi: 10.1016/j.cell.2015.04.036.

Authors

Emily K Lehrman¹, Beth Stevens²

Affiliations

¹ Department of Neurology, F.M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.
² Department of Neurology, F.M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA. Electronic address: [email protected].

PMID: 25957677
DOI: 10.1016/j.cell.2015.04.036

Abstract

Cancer is known for opportunistically utilizing resources from its surroundings for its own growth and survival. In this issue of Cell, Venkatesh et al. demonstrate that this also occurs in the brain, identifying neuronal activity-induced secretion of neuroligin-3 as a novel mechanism promoting glioma proliferation.

Publication types

Comment

MeSH terms

Animals
Brain Neoplasms / pathology*
Cell Adhesion Molecules, Neuronal / metabolism*
Cell Proliferation*
Glioma / pathology*
Humans
Male
Membrane Proteins / metabolism*
Nerve Tissue Proteins / metabolism*

Substances

Cell Adhesion Molecules, Neuronal
Membrane Proteins
Nerve Tissue Proteins
neuroligin 3