Bedside sonography by non-radiologists is rapidly expanding, presenting modern medicine with challenging professional, medico-legal, financial and logistic aspects. In the current article, we reviewed the relevant literature describing sonography application by internal medicine practitioners and the obstacles that may interfere with large-scale integration of point of care ultrasound imaging. In conclusion, we see a great potential for clinical benefit by internists who will use bedside sonography and we recommend establishing an official training program in the fiell of bedside ultrasonography by internists.