Assessment of Factors Affecting the Usefulness and Diagnostic Yield of Core Biopsy Needles with a Side Hole in Endoscopic Ultrasound-Guided Fine-Needle Aspiration

Gut Liver. 2016 Jan;10(1):51-7. doi: 10.5009/gnl14249.

Abstract

Background/aims: A barbed puncture needle with a side hole was recently developed to improve sample quality and quantity in endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA). In this study, we retrospectively assessed the usefulness of this puncture needle.

Methods: Factors affecting diagnostic yield, safety, and diagnostic accuracy were investigated in 76 patients who consecutively underwent EUS-FNA for neoplastic lesions at our hospital between January and December 2013.

Results: The procedure was successful in all cases; the rates of sample collection and determination of the correct diagnosis were 92.1% and 89.5%, respectively. The mean number of needle passes required for diagnosis was 1.1. Complications included mild intraluminal bleeding in two patients (2.6%). Multivariate analysis revealed that lesion size (≤20 mm) was significantly associated with a decreased chance of determining the correct diagnosis.

Conclusions: Core biopsy needles with a side hole are safe and provide a satisfactory diagnostic yield. However, the side hole may potentially reduce the rate of making the correct diagnosis in small lesions.

Keywords: Biopsy needles; Endoscopic ultrasound-guided fine needle aspiration; Side hole; Size of lesions.

Publication types

  • Evaluation Study

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Digestive System Neoplasms / diagnosis*
  • Digestive System Neoplasms / diagnostic imaging
  • Endoscopic Ultrasound-Guided Fine Needle Aspiration / instrumentation*
  • Equipment Design
  • Equipment Safety
  • Female
  • Gastrointestinal Tract / diagnostic imaging
  • Gastrointestinal Tract / pathology
  • Humans
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Needles / adverse effects
  • Needles / statistics & numerical data*
  • Predictive Value of Tests
  • Retrospective Studies
  • Sensitivity and Specificity
  • Statistics, Nonparametric