Prevalence and detection of psychosocial problems in cancer genetic counseling

Fam Cancer. 2015 Dec;14(4):629-36. doi: 10.1007/s10689-015-9809-9.

Abstract

Only a minority of individuals who undergo cancer genetic counseling experience heightened levels of psychological distress, but many more experience a range of cancer genetic-specific psychosocial problems. The aim of this study was to estimate the prevalence of such psychosocial problems, and to identify possible demographic and clinical variables associated significantly with them. Consenting individuals scheduled to undergo cancer genetic counseling completed the Psychosocial Aspects of Hereditary Cancer (PAHC) questionnaire, the Hospital Anxiety and Depression Scale (HADS) and the Distress Thermometer (DT) prior to or immediately following their counseling session. More than half of the 137 participants reported problems on three or more domains of the PAHC, most often in the domains 'living with cancer' (84%), 'family issues' (46%), 'hereditary predisposition' (45%), and 'child-related issues' (42%). Correlations between the PAHC, the HADS and the DT were low. Previous contact with a psychosocial worker, and having a personal history of cancer were associated significantly with HADS scores, but explained little variance (9%). No background variables were associated significantly with the DT. Previous contact with a psychosocial worker, and having children were significantly associated with several PAHC domains, again explaining only a small percentage of the variance (2-14%). The majority of counselees experience specific cancer genetic counseling-related psychosocial problems. Only a few background variables are associated significantly with distress or psychosocial problems. Thus we recommend using the PAHC or a similar problem-oriented questionnaire routinely in cancer genetic counseling to identify individuals with such problems.

Keywords: Distress; Genetic counseling; Hereditary cancer; Oncology; Psychosocial problems; Risk factors.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Anxiety / diagnosis*
  • Anxiety / epidemiology
  • Anxiety / psychology
  • Depression / diagnosis*
  • Depression / epidemiology
  • Depression / psychology
  • Female
  • Follow-Up Studies
  • Genetic Counseling / psychology*
  • Genetic Predisposition to Disease / psychology*
  • Humans
  • Male
  • Middle Aged
  • Neoplastic Syndromes, Hereditary / genetics
  • Neoplastic Syndromes, Hereditary / psychology*
  • Netherlands / epidemiology
  • Prevalence
  • Stress, Psychological / diagnosis*
  • Stress, Psychological / epidemiology
  • Stress, Psychological / psychology
  • Surveys and Questionnaires
  • Young Adult