Characterization of CMV-specific CD4+ T-cell reconstitution following stem cell transplantation through the use of HLA Class II-peptide tetramers identifies patients at high risk of recurrent CMV reactivation

Haematologica. 2015 Aug;100(8):e318-22. doi: 10.3324/haematol.2015.123687. Epub 2015 May 14.
No abstract available

Keywords: CD4; CD57; CMV; HLA-Class II tetramers; stem cell transplantation.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • CD4-Positive T-Lymphocytes / immunology*
  • CD4-Positive T-Lymphocytes / metabolism
  • Cytomegalovirus / immunology*
  • Cytomegalovirus Infections / immunology*
  • Epitopes, T-Lymphocyte / chemistry
  • Epitopes, T-Lymphocyte / immunology
  • Histocompatibility Antigens Class II / chemistry
  • Histocompatibility Antigens Class II / immunology*
  • Humans
  • Peptides / chemistry
  • Peptides / immunology*
  • Protein Multimerization
  • Stem Cell Transplantation* / adverse effects
  • T-Lymphocyte Subsets / immunology
  • T-Lymphocyte Subsets / metabolism
  • Transplantation, Homologous
  • Virus Activation / immunology*

Substances

  • Epitopes, T-Lymphocyte
  • Histocompatibility Antigens Class II
  • Peptides