Keywords: ATG101, autophagy-related 101; ATG13, autophagy-related 13; Huntingtin; Huntington disease; KO, knockout; MAP1LC3A, microtubule-associated protein 1 light chain 3 alpha; MAPT/Tau, microtubule-associated protein tau; MTOR, mechanistic target of rapamycin (serine/threonine kinase); MTORC1; MTORC1, MTOR complex 1; PRKAA/AMPK, protein kinase, AMP-activated, α catalytic subunit; RB1CC1, RB1-inducible coiled-coil 1; SQSTM1, sequestosome 1; SQSTM1/p62; ULK1; ULK1, unc-51 like autophagy activating kinase 1.; aggrephagy; cargo recognition; lipophagy; mitophagy; nonselective autophagy; selective autophagy.