Chemotherapy treatment of a pregnant woman with progressive gastric cancer

Intern Med. 2015;54(10):1207-12. doi: 10.2169/internalmedicine.54.3973. Epub 2015 May 15.

Abstract

We herein describe a rare case of gastric cancer that was treated with chemotherapy during pregnancy. A woman in her thirty's at 23 weeks of gestation was admitted to the hospital with epigastralgia and left cervical lymph node swelling. She had been previously diagnosed with metastatic adenocarcinoma at another hospital. Findings from a CT scan and esophagogastroduodenoscopy revealed progressive gastric cancer, and the pathology indicated poorly differentiated adenocarcinoma. Chemotherapy was administered at 24 weeks of gestation, without the development of severe toxicity. At 32 weeks of gestation, a healthy baby girl (birth weight 1,442 g, Apgar score 7/8) was delivered by caesarean section. The child continued to show no abnormalities at 12 months after delivery.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / drug therapy*
  • Adenocarcinoma / pathology
  • Adult
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Cesarean Section / methods*
  • Fatal Outcome
  • Female
  • Humans
  • Infant, Newborn
  • Meningeal Carcinomatosis / etiology
  • Paclitaxel / administration & dosage
  • Pregnancy
  • Pregnancy Complications, Neoplastic / drug therapy*
  • Pregnancy Complications, Neoplastic / pathology
  • Pregnancy Outcome
  • Stomach Neoplasms / drug therapy*
  • Stomach Neoplasms / pathology

Substances

  • Paclitaxel