Palmoplantar Pustular Psoriasis Is Associated with Missense Variants in CARD14, but Not with Loss-of-Function Mutations in IL36RN in European Patients

J Invest Dermatol. 2015 Oct;135(10):2538-2541. doi: 10.1038/jid.2015.186. Epub 2015 May 19.
No abstract available

Publication types

  • Comparative Study
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • CARD Signaling Adaptor Proteins / genetics*
  • Cohort Studies
  • Europe / epidemiology
  • Female
  • Genetic Predisposition to Disease / epidemiology*
  • Guanylate Cyclase / genetics*
  • Humans
  • Incidence
  • Interleukins / genetics*
  • Male
  • Mass Screening / methods
  • Membrane Proteins / genetics*
  • Middle Aged
  • Mutation, Missense*
  • Psoriasis / epidemiology
  • Psoriasis / genetics*

Substances

  • CARD Signaling Adaptor Proteins
  • IL36RN protein, human
  • Interleukins
  • Membrane Proteins
  • CARD14 protein, human
  • Guanylate Cyclase