The effect of diabetes mellitus on 30-day outcomes following single-level open lumbar microdiscectomy: an aged-matched case-control study

J Neurosurg Sci. 2017 Feb;61(1):1-7. doi: 10.23736/S0390-5616.16.03223-9. Epub 2015 May 20.

Abstract

Background: Diabetes mellitus (DM) is a known risk factor for post-surgical complications. However, few reports specifically study lumbar spine surgical outcomes in diabetics. The purpose of this study was to assess 30-day outcomes in patients with DM undergoing single-level open lumbar microdiscectomy (oLMD).

Methods: A retrospective case control study on patients with DM undergoing between 2001 and 2012. Patients who underwent a minimally invasive approach, repeat discectomy, or multilevel surgery were excluded. One hundred and twenty-six patients were age-matched with 126 non-diabetic controls. Outcomes assessed included length of stay (LOS), postoperative urinary retention (UR), total morbidity, infection, postoperative radiculitis, 30-day re-admissions and emergency department visits, and pain status at discharge and at 30 days. Categorical variables were evaluated with Pearson's χ2 tests. Student's t-tests were used to evaluate continuous variables. Univariate logistic regression was used to evaluate strength of association of DM with outcome variables.

Results: Mean LOS was significantly higher in diabetic patients (1.9 vs. 1.4 days, P<0.0001). DM was associated with increased morbidity (P=0.009, OR=3.3, CI: 1.3-9.5) and UR (P<0.0001, OR=8.2, CI: 3.4-24.8). No differences were found in 30-day readmission rates or emergency department visits, pain status at discharge and at 30 days, or postoperative radiculitis.

Conclusions: Overall, short-term outcomes are worse in patients with DM. Following single-level oLMD, DM is associated with longer hospital stays, UR, and increased morbidity. These short term outcomes consequently lead to an overall increase in hospital costs.

MeSH terms

  • Adult
  • Aged
  • Case-Control Studies
  • Diabetes Complications
  • Diabetes Mellitus / economics
  • Diabetes Mellitus / therapy
  • Diskectomy* / methods
  • Female
  • Hospital Costs / statistics & numerical data
  • Humans
  • Length of Stay
  • Lumbar Vertebrae / surgery*
  • Male
  • Middle Aged
  • Retrospective Studies
  • Risk Factors
  • Spinal Fusion / methods
  • Treatment Outcome