Does enzyme replacement therapy enhance brain-derived neurotrophic factor expression in Gaucher disease?

J Neuroimmunol. 2015 Jun 15:283:63. doi: 10.1016/j.jneuroim.2015.05.004. Epub 2015 May 5.

¹ Medical Genetics Service, Hospital de Clinicas de Porto Alegre, Rua Ramiro Barcelos, 2350 Porto Alegre, RS, Brazil; Post Graduation Program of Genetics and Molecular Biology, Universidade Federal do Rio Grande do Sul, Av. Bento Gonçalves, 9500 Porto Alegre, RS, Brazil; BRAIN Laboratory, Hospital de Clínicas de Porto Alegre, Rua Ramiro Barcelos, 2350 Porto Alegre, RS, Brazil.
² Post Graduation Program of Genetics and Molecular Biology, Universidade Federal do Rio Grande do Sul, Av. Bento Gonçalves, 9500 Porto Alegre, RS, Brazil; BRAIN Laboratory, Hospital de Clínicas de Porto Alegre, Rua Ramiro Barcelos, 2350 Porto Alegre, RS, Brazil.
³ Medical Genetics Service, Hospital de Clinicas de Porto Alegre, Rua Ramiro Barcelos, 2350 Porto Alegre, RS, Brazil.
⁴ CTN Diagnósticos, Av Ipiranga, 5000 Porto Alegre, RS, Brazil.
⁵ Medical Genetics Service, Hospital de Clinicas de Porto Alegre, Rua Ramiro Barcelos, 2350 Porto Alegre, RS, Brazil; BRAIN Laboratory, Hospital de Clínicas de Porto Alegre, Rua Ramiro Barcelos, 2350 Porto Alegre, RS, Brazil; Department of Genetics, Universidade Federal do Rio Grande do Sul, Av. Bento Gonçalves, 9500 Porto Alegre, RS, Brazil.

No abstract available

Keywords: BDNF; Gaucher disease; Glucocerebrosidase deficiency.

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