Mupirocin Resistance in Isolates of Staphylococcus spp. from Nasal Swabs in a Tertiary Hospital in France

J Clin Microbiol. 2015 Aug;53(8):2713-5. doi: 10.1128/JCM.00274-15. Epub 2015 May 27.

Abstract

Mupirocin is a topical antibiotic largely used to eradicate staphylococcal nasal carriage. Here, we investigated the prevalence of mupirocin-resistant Staphylococcus aureus and coagulase-negative staphylococcal isolates recovered from patients in different wards in a hospital (Lyon, France), which were determined both phenotypically with an Epsilometer test (Etest) and genetically by PCR for mupA and mupB.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / pharmacology*
  • Carrier State / epidemiology
  • Carrier State / microbiology*
  • Disk Diffusion Antimicrobial Tests
  • Drug Resistance, Bacterial*
  • France
  • Genes, Bacterial
  • Genotype
  • Humans
  • Mupirocin / pharmacology*
  • Nasal Mucosa / microbiology*
  • Phenotype
  • Polymerase Chain Reaction
  • Prevalence
  • Staphylococcal Infections / epidemiology
  • Staphylococcal Infections / microbiology*
  • Staphylococcus / drug effects*
  • Staphylococcus / isolation & purification
  • Tertiary Care Centers

Substances

  • Anti-Bacterial Agents
  • Mupirocin