A mitochondria-targeted colorimetric and ratiometric fluorescent probe for biological SO2 derivatives in living cells

Chem Commun (Camb). 2015 Jun 25;51(50):10236-9. doi: 10.1039/c5cc03055b. Epub 2015 May 29.

Abstract

A ratiometric fluorescent probe for SO2 derivatives based on the conjugate of carbazole and indolium was presented, which could selectively respond to HSO3(-) over other thiol compounds. More importantly, CZ-Id is a novel mitochondria-targeted ratiometric fluorescent probe to image exogenous SO2 derivatives.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Survival
  • Colorimetry
  • Fluorescent Dyes / chemistry*
  • HeLa Cells
  • Humans
  • Mitochondria / metabolism*
  • Sulfur Dioxide / chemistry*
  • Sulfur Dioxide / metabolism*

Substances

  • Fluorescent Dyes
  • Sulfur Dioxide