Novel HIV-1 Recombinant Identified in a Foreign Heterosexual Resident in Japan: Relatedness to Recently Reported CRF69_01B, Detected Primarily among Japanese Men Who Have Sex with Men

Shigeru Kusagawa; Yuko Yokota; Masayoshi Negishi; Makiko Kondo; Tetsuro Matano; Shingo Kato; Yutaka Takebe

doi:10.1128/genomeA.00196-15

Novel HIV-1 Recombinant Identified in a Foreign Heterosexual Resident in Japan: Relatedness to Recently Reported CRF69_01B, Detected Primarily among Japanese Men Who Have Sex with Men

Genome Announc. 2015 May 28;3(3):e00196-15. doi: 10.1128/genomeA.00196-15.

Authors

Shigeru Kusagawa¹, Yuko Yokota¹, Masayoshi Negishi², Makiko Kondo³, Tetsuro Matano¹, Shingo Kato⁴, Yutaka Takebe⁵

Affiliations

¹ AIDS Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
² Negishi Clinic, Tokyo, Japan.
³ Division of Microbiology, Kanagawa Prefectural Institute of Public Health, Kanagawa, Japan.
⁴ Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan.
⁵ AIDS Research Center, National Institute of Infectious Diseases, Tokyo, Japan [email protected].

Abstract

We report here an HIV-1 recombinant composed of CRF01_AE and subtype B, with a total of eight recombination breakpoints in the gag-pol and vpr-tat regions. This recombinant was identified from a Myanmarese heterosexual male in Japan and showed the chimera structure identical to recently reported CRF69_01B, detected primarily among men who have sex with men in Japan.