State of the art of leadless pacing

Europace. 2015 Oct;17(10):1508-13. doi: 10.1093/europace/euv096. Epub 2015 May 29.

Abstract

Despite undisputable benefits, conventional pacemaker therapy is associated with specific complications related to the subcutaneous device and the transvenous leads. Recently, two miniaturized leadless pacemakers, Nanostim™ (St. Jude Medical) and Micra™ (Medtronic), which can be completely implanted inside the right ventricle using steerable delivery systems, entered clinical application. The WiCS™-cardiac resynchronisation therapy (CRT) system (wireless cardiac stimulation for CRT, EBR Systems) delivers leadless left ventricular endocardial stimulation for cardiac resynchronization. In addition to obvious cosmetic benefits, leadless pacing systems may have the potential to overcome some complications of conventional pacing. However, acute and long-term complications still remains to be determined, as well as the feasibility of device explantation years after device placement.

Keywords: Catheter delivery; Leadless pacing; Pacemaker.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Cardiac Catheters / adverse effects*
  • Cardiac Resynchronization Therapy Devices / adverse effects*
  • Cardiac Resynchronization Therapy Devices / classification*
  • Endocardium / physiopathology*
  • Equipment Design
  • Heart Ventricles / physiopathology*
  • Humans
  • Prostheses and Implants
  • Treatment Outcome