Higher Levels of Serum Triglycerides were Associated with Postoperative Deep Vein Thrombosis After Total Hip Arthroplasty in Patients with Nontraumatic Osteonecrosis of the Femoral Head

Int J Low Extrem Wounds. 2016 Mar;15(1):41-4. doi: 10.1177/1534734615580017. Epub 2015 Jun 1.

Abstract

This retrospective study aimed to evaluate the association of serum lipids and deep vein thrombosis (DVT) risk following total hip arthroplasty (THA) in patients with nontraumatic osteonecrosis of the femoral head (ONFH). A total of 224 nontraumatic ONFH patients were enrolled. Serum levels of triglycerides (TG), total cholesterol, high-density lipoprotein cholesterol, and low-density lipoprotein cholesterol were detected preoperatively. All the patients underwent unilateral lower extremity venography on postoperative days 3 to 5 for DVT screening. In females, patients who were venogram positive for DVT had a higher serum TG level than those who were venogram negative for DVT (P = .029) and a higher TG level was associated with an increased DVT risk (P = .042). Serum TG levels considerably affect DVT risk after THA in female nontraumatic ONFH patients.

Keywords: arthroplasty; deep vein thrombosis; femoral head; lipids; osteonecrosis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Arthroplasty, Replacement, Hip*
  • Cholesterol / blood
  • Cohort Studies
  • Female
  • Femur Head Necrosis / blood*
  • Femur Head Necrosis / complications*
  • Humans
  • Male
  • Middle Aged
  • Postoperative Complications / blood*
  • Postoperative Complications / epidemiology*
  • Retrospective Studies
  • Risk Factors
  • Triglycerides / blood*
  • Venous Thrombosis / blood*
  • Venous Thrombosis / epidemiology*

Substances

  • Triglycerides
  • Cholesterol