Abstract
Particle-based delivery systems have a demonstrated value for drug discovery and development. Here, we report a new type of particle-based delivery system that has controllable release and is self-monitoring. The particles were composed of poly(N-isopropylacrylamide) (pNIPAM) hydrogel with an inverse opal structure. The presence of macropores in the particles provides channels for active drug loading and release from the materials.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Acrylic Resins / chemistry*
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Contrast Media / chemical synthesis*
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Delayed-Action Preparations / chemical synthesis*
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Diffusion
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Drug Monitoring / methods*
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Microscopy, Fluorescence / methods
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Nanocapsules / administration & dosage
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Nanocapsules / chemistry*
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Nanocapsules / ultrastructure
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Particle Size
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Theranostic Nanomedicine / methods
Substances
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Acrylic Resins
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Contrast Media
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Delayed-Action Preparations
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Nanocapsules
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poly-N-isopropylacrylamide