Atrial fibrillation (AF) is associated with an increased risk of stroke and mortality. Anticoagulation therapy reduces the risk of stroke in patients with AF. In a structured multidisciplinary AF-clinic correct anticoagulation treatment according to guidelines was achieved in 99% (170 out of 172 patients) compared to 79% (143 out of 179 patients) in the "usual care" period (p < 0.001). We propose establishment of structured multidisciplinary AF-clinics in Denmark to ensure optimal antithrombotic treatment and adherence to current guidelines.