Feasibility, safety, and short-term efficacy of the laparoscopic Nissen-Hill hybrid repair

Surg Endosc. 2016 Feb;30(2):551-558. doi: 10.1007/s00464-015-4238-2. Epub 2015 Jun 12.

Abstract

Background: A novel antireflux procedure combining laparoscopic Nissen fundoplication and Hill repair components was tested in 50 patients with paraesophageal hernia (PEH) and/or Barrett's esophagus (BE) because these two groups have been found to have a high rate of recurrence with conventional repairs.

Methods: Patients with symptomatic PEH and/or non-dysplastic BE underwent repair. Quality of life (QOL) metrics, manometry, EGD, and pH testing were administered pre- and postoperatively.

Results: Fifty patients underwent repair. There was no mortality and four major complications. At 13-month follow-up, there was one (2%) clinical recurrence, and two (4%) asymptomatic fundus herniations. Mean DeMeester scores improved from 57.2 to 7.7 (p < 0.0001). Control of preoperative symptoms was achieved in 90% with 6% resumption of antisecretory medication. All QOL metrics improved significantly.

Conclusions: The hybrid Nissen-Hill repair for patients with PEH and BE appears safe and clinically effective at short-term follow-up. It is hoped that the combined structural components may reduce the rate of recurrence compared to existing repairs.

Keywords: Antireflux surgery; Barrett’s metaplasia; Laparoscopic; Minimally invasive; Paraesophageal hernia repair.

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Barrett Esophagus / surgery*
  • Feasibility Studies
  • Female
  • Follow-Up Studies
  • Fundoplication / methods*
  • Hernia, Hiatal / surgery*
  • Humans
  • Laparoscopy / methods*
  • Male
  • Middle Aged
  • Patient Safety
  • Prospective Studies
  • Quality of Life
  • Recurrence
  • Treatment Outcome