Interobserver variation among pathologists for delineation of tumor on H&E-sections of laryngeal and hypopharyngeal carcinoma. How good is the gold standard?

Acta Oncol. 2016;55(3):391-5. doi: 10.3109/0284186X.2015.1049661. Epub 2015 Jun 13.

Authors

Elise Anne Jager¹, Stefan M Willems², Tim Schakel¹, Nina Kooij³, Pieter J Slootweg⁴, Marielle E P Philippens¹, Joana Caldas-Magalhaes¹, Chris H J Terhaard¹, Cornelis P J Raaijmakers¹

Affiliations

¹ a Department of Radiation Oncology , University Medical Center Utrecht , Utrecht , The Netherlands.
² b Department of Pathology , University Medical Center Utrecht , Utrecht , The Netherlands.
³ c Department of Pathology , Laboratory Oost-Nederland , Hengelo , The Netherlands.
⁴ d Department of Pathology , Radboud University Medical Center , Nijmegen , the Netherlands.

PMID: 26073449
DOI: 10.3109/0284186X.2015.1049661

No abstract available

Publication types

Letter
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

MeSH terms

Carcinoma, Squamous Cell / diagnosis*
Eosine Yellowish-(YS) / chemistry
Hematoxylin / chemistry
Humans
Hypopharyngeal Neoplasms / diagnosis*
Image Processing, Computer-Assisted / methods
Laryngeal Neoplasms / diagnosis*
Neoplasm Staging
Observer Variation*
Prognosis
Staining and Labeling / methods*

Substances

Eosine Yellowish-(YS)
Hematoxylin