Rare cause of jaundice in a post liver transplant patient

Transpl Infect Dis. 2015 Aug;17(4):579-82. doi: 10.1111/tid.12414. Epub 2015 Jul 16.

Abstract

A hepatitis B virus carrier suffering from acute flare of chronic hepatitis B infection underwent deceased-donor liver transplantation. He was put on the immunosuppressive agent tacrolimus. On routine follow-up, he was found to have abnormal liver function. Computed tomography scan of the abdomen did not show any dilatation of the biliary system. Liver biopsy showed scattered microabscesses, and a microgranuloma was detected. Endoscopic retrograde cholangiography was performed and a biliary anastomotic stricture (BAS) was noted. In addition, the Chinese liver fluke, Clonorchis sinensis, was discovered. Balloon dilatation and stenting were performed. The patient was given a course of praziquantel. His liver function improved and normalized. We present the case of a liver transplant recipient with cholangitis caused by C. sinensis infestation and infection and biliary obstruction resulting from BAS.

Keywords: Clonorchis sinensis; biliary anastomotic stricture; deceased-donor liver transplantation.

Publication types

  • Case Reports

MeSH terms

  • Cholangitis / diagnosis
  • Cholangitis / parasitology*
  • Clonorchiasis / diagnosis*
  • Clonorchiasis / etiology
  • Humans
  • Jaundice / diagnosis
  • Jaundice / parasitology*
  • Liver Transplantation*
  • Male
  • Postoperative Complications / diagnosis*
  • Postoperative Complications / parasitology