Pharmacist intervention for blood pressure control: medication intensification and adherence

J Am Soc Hypertens. 2015 Jul;9(7):569-78. doi: 10.1016/j.jash.2015.05.005. Epub 2015 May 15.

Abstract

The objective of this study was to describe medication adherence and medication intensification in a physician-pharmacist collaborative management (PPCM) model compared with usual care. This study was a prospective, cluster, randomized study in 32 primary care offices from 15 states. The primary outcomes were medication adherence and anti-hypertensive medication changes during the first 9 months of the intervention. The 9-month visit was completed by 539 patients, 345 of which received the intervention. There was no significant difference between intervention and usual care patients in regards to medication adherence at 9 months. Intervention patients received significantly more medication changes (4.9 vs.1.1; P = .0003) and had significantly increased use of diuretics and aldosterone antagonists when compared with usual care (P = .01).The PPCM model increased medication intensification; however, no significant change in medication adherence was detected. PPCM models will need to develop non-adherence identification and intervention methods to further improve the potency of the care team.

Keywords: Collaboration; hypertension; team-based care.

Publication types

  • Multicenter Study
  • Randomized Controlled Trial

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Antihypertensive Agents / therapeutic use*
  • Cooperative Behavior
  • Diuretics / therapeutic use
  • Drug Information Services
  • Female
  • Humans
  • Male
  • Medication Adherence*
  • Middle Aged
  • Mineralocorticoid Receptor Antagonists / therapeutic use
  • Patient Education as Topic
  • Pharmacists*
  • Primary Health Care*
  • Prospective Studies
  • United States
  • Young Adult

Substances

  • Antihypertensive Agents
  • Diuretics
  • Mineralocorticoid Receptor Antagonists