A "normal" invasive coronary angiogram may not be normal

Bjarne L Nørgaard; Nicolaj C Hansson; Evald H Christiansen; Anne Kaltoft; Hans Erik Bøtker; Jens F Lassen; Michael Mæng; Jesper M Jensen

doi:10.1016/j.jcct.2015.05.003

A "normal" invasive coronary angiogram may not be normal

J Cardiovasc Comput Tomogr. 2015 Jul-Aug;9(4):264-6. doi: 10.1016/j.jcct.2015.05.003. Epub 2015 May 14.

Authors

Bjarne L Nørgaard¹, Nicolaj C Hansson², Evald H Christiansen², Anne Kaltoft², Hans Erik Bøtker², Jens F Lassen², Michael Mæng², Jesper M Jensen²

Affiliations

¹ Department of Cardiology, Aarhus University Hospital Skejby, Skejby, Aarhus N, Aarhus DK-8200, Denmark. Electronic address: [email protected].
² Department of Cardiology, Aarhus University Hospital Skejby, Skejby, Aarhus N, Aarhus DK-8200, Denmark.

PMID: 26088376
DOI: 10.1016/j.jcct.2015.05.003

Abstract

In clinical practice, a normal or near-normal invasive coronary angiogram is considered to be reliable evidence for the absence of hemodynamically significant coronary artery disease. We present 2 patients with near-normal coronary angiograms who had noninvasive evidence of vessel-specific ischemia confirmed by invasive measurement of fractional flow reserve.

Keywords: Computed tomography; Coronary angiography; Coronary artery disease; Coronary plaque; Fractional flow reserve.

Publication types

Case Reports
Video-Audio Media

MeSH terms

Coronary Angiography / methods*
Coronary Artery Disease / complications
Coronary Artery Disease / diagnostic imaging*
Coronary Artery Disease / physiopathology*
False Negative Reactions
Fractional Flow Reserve, Myocardial
Humans
Male
Middle Aged
Myocardial Ischemia / diagnostic imaging*
Myocardial Ischemia / etiology
Myocardial Ischemia / physiopathology*
Radiographic Image Enhancement / methods
Reference Values
Reproducibility of Results
Sensitivity and Specificity
Tomography, X-Ray Computed / methods*