Molecular Characterization of the First Ebola Virus Isolated in Italy, from a Health Care Worker Repatriated from Sierra Leone

Concetta Castilletti; Fabrizio Carletti; Cesare E M Gruber; Licia Bordi; Eleonora Lalle; Serena Quartu; Silvia Meschi; Daniele Lapa; Francesca Colavita; Roberta Chiappini; Antonio Mazzarelli; Patrizia Marsella; Nicola Petrosillo; Emanuele Nicastri; Giovanni Chillemi; Alessio Valentini; Alessandro Desideri; Antonino Di Caro; Giuseppe Ippolito; Maria R Capobianchi

doi:10.1128/genomeA.00639-15

Molecular Characterization of the First Ebola Virus Isolated in Italy, from a Health Care Worker Repatriated from Sierra Leone

Genome Announc. 2015 Jun 18;3(3):e00639-15. doi: 10.1128/genomeA.00639-15.

Authors

Concetta Castilletti¹, Fabrizio Carletti¹, Cesare E M Gruber¹, Licia Bordi¹, Eleonora Lalle¹, Serena Quartu¹, Silvia Meschi¹, Daniele Lapa¹, Francesca Colavita¹, Roberta Chiappini¹, Antonio Mazzarelli¹, Patrizia Marsella¹, Nicola Petrosillo¹, Emanuele Nicastri¹, Giovanni Chillemi², Alessio Valentini, Alessandro Desideri, Antonino Di Caro¹, Giuseppe Ippolito¹, Maria R Capobianchi³

Affiliations

¹ National Institute for Infectious Diseases L. Spallanzani, Rome, Italy.
² CINECA, Rome, Italy.
³ National Institute for Infectious Diseases L. Spallanzani, Rome, Italy [email protected].

Abstract

Here, we report the complete genome sequence of an Ebola virus (EBOV) isolated from a health worker repatriated from Sierra Leone to Italy in November 2014. The sequence, clustering in clade 3 of the Sierra Leone sequences, was analyzed with respect to mutations possibly affecting diagnostic and therapeutic targets as well as virulence.