A Sandwich Technique for Prevention of Cerebrospinal Fluid Rhinorrhea and Reconstruction of the Sellar Floor after Microsurgical Transsphenoidal Pituitary Surgery

J Neurol Surg A Cent Eur Neurosurg. 2016 May;77(3):229-32. doi: 10.1055/s-0035-1547357. Epub 2015 Jun 19.

Abstract

Background: Cerebrospinal fluid (CSF) leaks are a well-known complication of transsphenoidal surgery. Several autologous and artificial grafts have been used to close the sellar floor in an attempt to prevent postoperative CSF rhinorrhea.

Objective: To evaluate and describe a sandwich technique to close the sellar floor using autologous bone, absorbable gelatin sponge, and coated collagen fleece.

Methods: We reviewed 50 consecutive patients between April 2010 and August 2011 who underwent transsphenoidal surgery ending with reconstruction of the sellar floor with a particular sandwich technique. Patients with an intraoperative CSF leak received an additional lumbar drain.

Results: There were no cases of CSF rhinorrhea at postoperative follow-up after 6 weeks and no revision surgery.

Conclusion: The proposed sandwich technique for closure of the sellar floor to the sphenoid sinus is a suitable alternative to autologous grafts and seems to be effective in preventing CSF rhinorrhea.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Cerebrospinal Fluid Rhinorrhea / etiology
  • Cerebrospinal Fluid Rhinorrhea / prevention & control*
  • Female
  • Humans
  • Male
  • Microsurgery / adverse effects
  • Microsurgery / methods*
  • Middle Aged
  • Pituitary Gland / surgery*
  • Plastic Surgery Procedures / adverse effects
  • Plastic Surgery Procedures / methods*
  • Postoperative Complications / etiology
  • Postoperative Complications / prevention & control*
  • Retrospective Studies
  • Sella Turcica / surgery*
  • Sphenoid Sinus / surgery*
  • Treatment Outcome
  • Young Adult