[Relation between the changes in evoked and constant potentials of the brain and emotional disorders in Alzheimer's disease]

Zh Nevropatol Psikhiatr Im S S Korsakova. 1989;89(9):92-7.
[Article in Russian]

Abstract

The visual evoked potentials (VEP), brain DC potential (DP) mapping and emotional disorders were comparatively evaluated in patients with Alzheimer's disease (AD) and age-matched healthy individuals. In AD, the severity of emotional disorders correlated with the reduction of VEP late components P 4 N 4. In patients with frequent affect oscillations, the amplitude of N 3 component of the VEP and its variability was higher than in patients with rare undulations of the emotional state. In AD patients the DP levels were increased as compared to normal levels in all the brain sites investigated. The degree of emotional disorders in AD patients positively correlated with frontal DP levels. The rise in frontal DP levels and decrease in late VEP components were interrelated in AD patients.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Action Potentials / physiology
  • Aged
  • Alzheimer Disease / complications
  • Alzheimer Disease / physiopathology*
  • Alzheimer Disease / psychology
  • Cerebral Cortex / physiopathology*
  • Evoked Potentials, Visual / physiology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Mood Disorders / etiology*
  • Mood Disorders / physiopathology
  • Reference Values