A case of primary pancreatic non-Hodgkin B-cell lymphoma mimicking autoimmune pancreatitis

J Gastrointestin Liver Dis. 2015 Jun;24(2):245-8. doi: 10.15403/jgld.2014.1121.hdk.

Abstract

Non Hodgkin lymphoma frequently involves the gastrointestinal tract, in particular the stomach and the small bowel. Rarely, it can also be a cause of pancreatic masses. Clinical presentation is often non-specific and may overlap with other pancreatic conditions such as carcinoma, neuroendocrine tumours and autoimmune pancreatitis. We report a case of primary pancreatic lymphoma in a young woman with jaundice, fever and abdominal pain mimicking autoimmune pancreatitis. Clinical evaluation included the abdominal Computed Tomography scan, Magnetic Resonance Imaging and an upper gastrointestinal endoscopy that revealed a large duodenal mass. Endoscopic biopsies were performed and eventually histological examination was coherent with a diagnosis of primary pancreatic lymphoma.

Publication types

  • Case Reports

MeSH terms

  • Abdominal Pain / diagnosis
  • Abdominal Pain / etiology
  • Adult
  • Antigens, CD20 / analysis
  • Antineoplastic Agents / therapeutic use
  • Autoimmune Diseases / diagnosis*
  • Biomarkers, Tumor / analysis
  • Biopsy
  • Diagnosis, Differential
  • Diagnostic Errors
  • Diagnostic Imaging / methods
  • Endoscopy, Digestive System
  • Female
  • Fever / diagnosis
  • Fever / etiology
  • Humans
  • Immunohistochemistry
  • Jaundice / diagnosis
  • Jaundice / etiology
  • Lymphoma, B-Cell / complications
  • Lymphoma, B-Cell / diagnosis*
  • Lymphoma, B-Cell / drug therapy
  • Lymphoma, B-Cell / immunology
  • Magnetic Resonance Imaging
  • Pancreatic Neoplasms / complications
  • Pancreatic Neoplasms / diagnosis*
  • Pancreatic Neoplasms / drug therapy
  • Pancreatic Neoplasms / immunology
  • Pancreatitis / diagnosis*
  • Predictive Value of Tests
  • Tomography, X-Ray Computed

Substances

  • Antigens, CD20
  • Antineoplastic Agents
  • Biomarkers, Tumor