Prevalence of zoonotic visceral leishmaniasis in dogs in an endemic area of Brazil

Rev Soc Bras Med Trop. 2015 Jul-Aug;48(4):491-3. doi: 10.1590/0037-8682-0224-2014. Epub 2015 Jun 26.

Abstract

Introduction: The northeast region of Brazil is endemic for zoonotic visceral leishmaniasis (ZVL). The aim of this study was to determine the prevalence of infection in dogs in Petrolina.

Methods: Blood samples were collected from dogs (n = 600), and bone-marrow biopsy was performed in animals with positive serological test results that presented clinical signs of ZVL. The serological analyses were performed using an enzyme-linked immunosorbent assay (ELISA) (S7(r)Biogene).

Results: Of the 600 dogs tested, 19% (115/600) presented anti-L. infantum chagasi antibodies.

Conclusions: Our data are important because canine infection is an important risk factor for the human disease.

MeSH terms

  • Animals
  • Antibodies, Protozoan / blood*
  • Brazil / epidemiology
  • Dog Diseases / diagnosis
  • Dog Diseases / epidemiology*
  • Dogs
  • Endemic Diseases
  • Enzyme-Linked Immunosorbent Assay / veterinary
  • Female
  • Leishmania infantum / immunology*
  • Leishmaniasis, Visceral / diagnosis
  • Leishmaniasis, Visceral / epidemiology
  • Leishmaniasis, Visceral / veterinary*
  • Male
  • Prevalence
  • Rural Population
  • Urban Population

Substances

  • Antibodies, Protozoan