Sleep-disordered breathing and future cardiovascular disease risk

Semin Perinatol. 2015 Jun;39(4):304-9. doi: 10.1053/j.semperi.2015.05.010. Epub 2015 Jul 2.

Abstract

Sleep-disordered breathing occurs in 0.6-15% of reproductive age women. This condition is associated with an increased lifetime risk of cardiovascular disease, cardiovascular mortality, and all-cause mortality. A substantial body of evidence demonstrated increased perinatal morbidity among pregnancies affected by SDB including gestational diabetes, gestational hypertension, and preeclampsia. These same conditions are predictive of later cardiovascular disease. Treatment of SDB has been demonstrated to decrease future cardiovascular events and mortality. Screening at-risk individuals in the perinatal period can identify women with SDB, who can benefit from treatment. Continuous positive airway pressure and lifestyle interventions can decrease subsequent adverse cardiovascular health outcomes.

Keywords: obesity; preeclampsia; sleep apnea; sleep disorderd breathing.

Publication types

  • Review

MeSH terms

  • Adult
  • Body Mass Index
  • Cardiovascular Diseases / etiology
  • Cardiovascular Diseases / mortality
  • Cardiovascular Diseases / prevention & control*
  • Comorbidity
  • Continuous Positive Airway Pressure
  • Directive Counseling / methods*
  • Early Diagnosis
  • Female
  • Humans
  • Polysomnography
  • Risk Factors
  • Risk Reduction Behavior
  • Sleep Apnea Syndromes / diagnosis*
  • Sleep Apnea Syndromes / etiology
  • Sleep Apnea Syndromes / mortality
  • United States / epidemiology