Sclerosing Paragangliomas of the Carotid Body: A Series of a Rare Variant and Review of the Literature

Eugene Ng; Gemma Duncan; Andrew M T L Choong; Leo Francis; Wallace Foster; Allan Kruger

doi:10.1016/j.avsg.2015.04.083

Sclerosing Paragangliomas of the Carotid Body: A Series of a Rare Variant and Review of the Literature

Ann Vasc Surg. 2015 Oct;29(7):1454.e5-1454.e12. doi: 10.1016/j.avsg.2015.04.083. Epub 2015 Jul 3.

Authors

Eugene Ng¹, Gemma Duncan², Andrew M T L Choong³, Leo Francis⁴, Wallace Foster⁵, Allan Kruger⁵

Affiliations

¹ Department of Vascular Surgery, Royal Brisbane & Women's Hospital, Herston, QLD, Australia. Electronic address: [email protected].
² Department of Vascular Surgery, Royal Brisbane & Women's Hospital, Herston, QLD, Australia.
³ Department of Vascular Surgery, Royal Brisbane & Women's Hospital, Herston, QLD, Australia; Discipline of Surgery, University of Queensland, Brisbane, QLD, Australia; School of Medicine, Griffith University, Gold Coast, QLD, Australia.
⁴ Department of Pathology, Royal Brisbane & Women's Hospital, Herston, QLD, Australia.
⁵ Department of Vascular Surgery, Royal Brisbane & Women's Hospital, Herston, QLD, Australia; Vascular Surgery, Greenslopes Private Hospital, Brisbane, QLD, Australia.

PMID: 26146236
DOI: 10.1016/j.avsg.2015.04.083

Abstract

The incidence of carotid body tumors is less than 1 in 30,000. Histologically, they present with a classic pattern of tumor cells arranged in "zellballen" or nests. A new extremely rare sclerosing subtype has been described in the literature with distinct stromal sclerosis and hyalinization, differentiating it from conventional paragangliomata. We present a case series of 3 patients with this rare variant and also discuss the diagnosis and management of carotid body parangliomas.

Publication types

Case Reports
Review

MeSH terms

Adult
Aged
Carotid Arteries / pathology*
Carotid Arteries / surgery
Carotid Body Tumor / pathology*
Female
Humans
Ligation
Male
Saphenous Vein / transplantation
Sclerosis