Early post mortem expression of genes related to tenderization in two Italian Simmental young bulls' skeletal muscles differing in contractile type

Anim Sci J. 2015 Dec;86(12):992-9. doi: 10.1111/asj.12386. Epub 2015 Jul 8.

Abstract

The early post mortem expression of eight genes potentially involved in meat ageing process and the tenderness of two Italian Simmental young bulls' (Bos taurus) skeletal muscles differing in their contractile type were evaluated. Samples of Longissimus lumborum (LL) and Infraspinatus (IS) muscles were collected from 17 bulls. The messenger RNA (mRNA) abundances of calpain-1, calpain-2, calpastatin, caspase 3, caspase 9, heat shock protein 27 (Hsp27), Hsp40 and Hsp70 were detected by quantitative PCR. The myosin heavy chain-slow and -fast isoform content, the pH48h and the lipid content of the muscles were in line with the contractile and metabolic type. In comparison with the fast LL, the slow IS showed a lower calpain-1/calpastatin mRNA content ratio after slaughtering and a higher Warner-Bratzler Initial Yield value after 7 days of ageing. Hsp27 and Hsp70 mRNA abundances were significantly lower in LL than IS, highlighting their potential role in the ageing process of bovine muscles.

Keywords: Warner Bratzler shear force; calpain; calpastatin; caspase; heat shock protein.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Calpain / genetics
  • Calpain / metabolism
  • Caspases / genetics
  • Caspases / metabolism
  • Cattle / genetics*
  • Chemical Phenomena
  • Food Quality*
  • Gene Expression*
  • Heat-Shock Proteins / genetics
  • Heat-Shock Proteins / metabolism
  • Male
  • Meat*
  • Muscle Contraction / genetics*
  • Muscle, Skeletal / metabolism*
  • Myosin Heavy Chains / genetics
  • Myosin Heavy Chains / metabolism
  • Polymerase Chain Reaction / methods
  • Postmortem Changes*
  • RNA, Messenger / analysis
  • Shear Strength
  • Time Factors

Substances

  • Heat-Shock Proteins
  • RNA, Messenger
  • Calpain
  • Caspases
  • Myosin Heavy Chains