Gamma-carboline inhibits neurodegenerative processes in a transgenic model of amyotrophic lateral sclerosis

Dokl Biochem Biophys. 2015:462:189-92. doi: 10.1134/S1607672915030138. Epub 2015 Jul 12.

Authors

E V Bronovitsky¹, A V Deikin, T G Ermolkevich, A B Elyakov, E N Fedorov, E R Sadchikova, I L Goldman, R K Ovchinnikov, A Yu Roman, I V Khritankova, M S Kukharsky, V L Buchman, S O Bachurin, A A Ustyugov

Affiliation

¹ Institute of Physiologically Active Compounds, Russian Academy of Sciences, Severnyi proezd 1, Chernogolovka, Moscow oblast, 142432, Russia, [email protected].

PMID: 26163217
DOI: 10.1134/S1607672915030138

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amyotrophic Lateral Sclerosis / drug therapy*
Animals
Carbolines / pharmacology*
Carbolines / therapeutic use
Disease Models, Animal
Male
Mice
Mice, Transgenic
RNA-Binding Protein FUS / genetics
Survival Analysis

Substances

Carbolines
RNA-Binding Protein FUS
gamma-carboline