The GLV6/RGF8/CLEL2 peptide regulates early pericycle divisions during lateral root initiation

J Exp Bot. 2015 Aug;66(17):5245-56. doi: 10.1093/jxb/erv329. Epub 2015 Jul 10.

Abstract

Small peptides of the Arabidopsis GLV/RGF/CLEL family are involved in different developmental programmes, including meristem maintenance and gravitropic responses. In addition, our previous report suggested that they also participate in the formation of lateral roots. Specifically, GLV6 is transcribed during the first stages of primordium development and GLV6 overexpression results in a strong reduction of emerged lateral roots. To investigate the cause of this phenotype we analysed primordium development in gain-of-function (gof) mutants and found that GLV6 induces supernumerary pericycle divisions, hindering the formation of a dome-shaped primordium, a prerequisite for successful emergence. The GLV6 phenotype could be reproduced by ectopic expression of the gene only in xylem-pole pericycle cells. Furthermore, GLV6 seems to function at the very beginning of lateral root initiation because GLV6 excess-either gene overexpression or peptide treatment-disrupts the first asymmetric cell divisions required for proper primordium formation. Our results suggest that GLV6 acts during lateral root initiation controlling the patterning of the first pericycle divisions.

Keywords: Arabidopsis thaliana; Asymmetric division; CLE-like; GOLVEN; lateral root development; primordium initiation; root growth factors; secreted peptides..

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Arabidopsis / genetics*
  • Arabidopsis / growth & development
  • Arabidopsis / metabolism
  • Arabidopsis Proteins / genetics*
  • Arabidopsis Proteins / metabolism
  • Gene Expression Regulation, Plant*
  • Intracellular Signaling Peptides and Proteins / genetics*
  • Intracellular Signaling Peptides and Proteins / metabolism
  • Plant Roots / genetics*
  • Plant Roots / growth & development
  • Plant Roots / metabolism
  • Transcription, Genetic

Substances

  • Arabidopsis Proteins
  • GLV6 peptide, Arabidopsis
  • Intracellular Signaling Peptides and Proteins