Evidence-based care pathway for cellulitis improves process, clinical, and cost outcomes

J Hosp Med. 2015 Dec;10(12):780-6. doi: 10.1002/jhm.2433. Epub 2015 Jul 28.

Abstract

Background: Cellulitis is a common infection with wide variation of clinical care.

Objective: To implement an evidence-based care pathway and evaluate changes in process metrics, clinical outcomes, and cost for cellulitis.

Design: A retrospective observational pre-/postintervention study was performed.

Setting: University of Utah Health Care, a 500-bed academic medical center in Salt Lake City, Utah.

Patients: All patients 18 years or older admitted to the emergency department observation unit or hospital with a primary diagnosis of cellulitis.

Intervention: Development of an evidence-based care pathway for cellulitis embedded into the electronic medical record with education for all emergency and internal medicine physicians.

Measurements: Primary outcome of broad-spectrum antibiotic use. Secondary outcomes of computed tomography/magnetic resonance imaging orders, length of stay (LOS), 30-day readmission, and pharmacy, lab, imaging, and total facility costs.

Results: A total of 677 visits occurred, including 370 visits where order sets were used. Among all patients, there was a 59% decrease in the odds of ordering broad-spectrum antibiotics (P < 0.001), 23% decrease in pharmacy cost (P = 0.002), and 13% decrease in total facility cost (P = 0.006). Compared to patients for whom order sets were not used, patients for whom order sets were used had a 75%, 13%, and 25% greater decrease in the odds of ordering broad-spectrum antibiotics (P < 0.001), clinical LOS (P = 0.041), and pharmacy costs (P = 0.074), respectively.

Conclusion: The evidence-based care pathway for cellulitis improved care at an academic medical center by reducing broad-spectrum antibiotic use, pharmacy costs, and total facility costs without an adverse change in LOS or 30-day readmissions.

Publication types

  • Observational Study

MeSH terms

  • Academic Medical Centers / economics*
  • Adult
  • Aged
  • Anti-Bacterial Agents / economics
  • Anti-Bacterial Agents / therapeutic use
  • Cellulitis / diagnosis
  • Cellulitis / drug therapy
  • Cellulitis / economics*
  • Cost-Benefit Analysis* / standards
  • Evidence-Based Medicine / economics*
  • Evidence-Based Medicine / standards
  • Female
  • Hospital Costs* / standards
  • Humans
  • Male
  • Middle Aged
  • Pharmacy Service, Hospital / economics
  • Pharmacy Service, Hospital / standards
  • Process Assessment, Health Care / economics*
  • Process Assessment, Health Care / standards
  • Retrospective Studies

Substances

  • Anti-Bacterial Agents