Modification of the bacterial adhesion of Staphylococcus aureus by antioxidant blooming on polyurethane films

Mater Sci Eng C Mater Biol Appl. 2015 Nov 1:56:522-31. doi: 10.1016/j.msec.2015.07.009. Epub 2015 Jul 15.

Abstract

Medical device-related infections are a major problem in hospital. The risk of developing an infection is linked to the bacterial adhesion ability of pathogen strains on the device and their ability to form a biofilm. Here we focused on polymer surfaces exhibiting a blooming of antioxidant (Irganox 3114® and Irganox 1076®) on their surface. We tried to put into evidence the effect of such a phenomenon on the bacterial adhesion in terms of number of viable cultivable bacteria and bacteria localization on the surface. We showed that the blooming has a tendency to increase the Staphylococcus aureus adhesion phenomenon in part for topographic reasons.

Keywords: AFM; Antioxidant; Bacterial adhesion; Blooming; Polyurethane; Staphylococcus aureus.

MeSH terms

  • Antioxidants / chemistry*
  • Bacterial Adhesion*
  • Biofilms / growth & development*
  • Butylated Hydroxytoluene / analogs & derivatives
  • Butylated Hydroxytoluene / chemistry
  • Membranes, Artificial*
  • Polyurethanes / chemistry*
  • Staphylococcus aureus / physiology*

Substances

  • Antioxidants
  • Irganox 3114
  • Membranes, Artificial
  • Polyurethanes
  • Butylated Hydroxytoluene
  • Irganox 1076