Plant uptake of pharmaceutical and personal care products from recycled water and biosolids: a review

Reuse of treated wastewater for agricultural irrigation is growing in arid and semi-arid regions, while increasing amounts of biosolids are being applied to fields to improve agricultural outputs. These historically under-utilized resources contain "emerging contaminants", such as pharmaceutical and personal care products (PPCPs), which may enter agricultural soils and potentially contaminate food crops. In this review, we summarize recent research and provide a detailed overview of PPCPs in the soil-plant systems, including analytical methods for determination of PPCPs in plant tissues, fate of PPCPs in agricultural soils receiving treated wastewater irrigation or biosolids amendment, and plant uptake of PPCPs under laboratory and field conditions. Mechanisms of uptake and translocation of PPCPs and their metabolisms in plants are also reviewed. Field studies showed that the concentration levels of PPCPs in crops that were irrigated with treated wastewater or applied with biosolids were very low. Potential human exposure to PPCPs through dietary intake was discussed. Information gaps and questions for future research have been identified in this review.