[Computed Tomography-Based Planimetry of the Pancreatic Transection Line in Risk Evaluation for Postoperative Pancreatic Fistula after Pancreatic Head Resection]

Zentralbl Chir. 2016 Aug;141(4):446-53. doi: 10.1055/s-0035-1546193. Epub 2015 Aug 10.
[Article in German]

Abstract

Background: Postoperative pancreatic fistula is a relevant complication after pancreatoduodenectomy. Therefore, preoperative detection of high risk patients may be important. We evaluated preoperative CT-imaging by planimetry at the expected resection plane along the superior mesenteric vein and correlated the results with the incidence of postoperative pancreatic fistula.

Patients and methods: From 2009 to 2013, 123 patients with pancreatoduodenectomy underwent homogenous preoperative imaging and reconstruction of the pancreatojejunostomy. Planimetry was performed at a multiplanar reconstruction of the pancreatic transection plane (diameter, range, duct width, area) as well as the calculation of ratios (duct width/pancreatic diameter; D/P-ratio). The measured values were correlated with the incidence of postoperative pancreatic fistula.

Results: Planimetry showed a significant difference of the pancreatic transection plane in relation to the incidence of postoperative pancreatic fistula. A thick parenchyma and a tiny duct are significant risk factors. In 84 % or, respectively, 94 % of the patients with postoperative pancreatic fistula, a duct width of less than 20 % of the pancreatic diameter was observed (D/P ratio < 0.2; p < 0.01). The D/P ratio was the only independent risk factor in multivariate analysis.

Discussion: The incidence of postoperative pancreatic fistula correlates significantly with the morphology of the pancreatic transection plane. The risk increases significantly with a D/P ratio of < 0.2.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Anastomosis, Surgical / methods
  • Female
  • Humans
  • Image Interpretation, Computer-Assisted / methods*
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Pancreas / diagnostic imaging*
  • Pancreas / pathology
  • Pancreas / surgery*
  • Pancreatic Diseases / diagnostic imaging*
  • Pancreatic Diseases / pathology
  • Pancreatic Diseases / surgery*
  • Pancreatic Fistula / etiology*
  • Pancreatic Neoplasms / diagnostic imaging*
  • Pancreatic Neoplasms / pathology
  • Pancreatic Neoplasms / surgery*
  • Pancreaticojejunostomy / methods
  • Postoperative Complications / etiology*
  • Retrospective Studies
  • Risk Assessment / methods*
  • Stomach / diagnostic imaging
  • Stomach / pathology
  • Stomach / surgery
  • Suture Techniques
  • Tomography, X-Ray Computed / methods*