Pulmonary arterial hypertension in a child with stage-IV neuroblastoma after autologous hematopoietic stem cell transplantation and review of the literature

Pediatr Transplant. 2015 Nov;19(7):E185-8. doi: 10.1111/petr.12576. Epub 2015 Aug 18.

Abstract

PH is a rare condition with high mortality rate after pediatric HSCT. As clinical presentation is non-specific and may mimic other conditions, a high degree of suspicion is required for diagnosis. Here, we present a patient with stage-IV neuroblastoma who developed PAH after autologous HSCT. After exclusion of other causes of PH, we regarded that this condition was secondary to HSCT.

Keywords: children; hematopoietic stem cell transplantation; pulmonary hypertension.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Child, Preschool
  • Hematopoietic Stem Cell Transplantation / adverse effects*
  • Humans
  • Hypertension, Pulmonary / diagnosis
  • Hypertension, Pulmonary / etiology*
  • Male
  • Neoplasm Staging
  • Neuroblastoma / pathology
  • Neuroblastoma / therapy*
  • Transplantation, Autologous