Hyper-activated PI3K-δ in immunodeficiency

Oncotarget. 2015 Jul 30;6(21):18242-3. doi: 10.18632/oncotarget.4884.

Authors

Lucie Heurtier¹, Marie-Céline Deau¹, Sven Kracker¹

Affiliation

¹ Université Paris Descartes, Sorbonne Paris Cité, Imagine Institute, INSERM UMR 1163, Human Lymphohematopoiesis Laboratory, Paris, France.

No abstract available

Publication types

Editorial

MeSH terms

Class I Phosphatidylinositol 3-Kinases / genetics*
Class I Phosphatidylinositol 3-Kinases / metabolism
Class Ia Phosphatidylinositol 3-Kinase
Enzyme Activation / genetics
Genetic Predisposition to Disease / genetics*
Humans
Immunologic Deficiency Syndromes / genetics*
Immunologic Deficiency Syndromes / metabolism
Lymphocytes / metabolism
Mutation, Missense*
Phosphatidylinositol 3-Kinases / genetics
Phosphatidylinositol 3-Kinases / metabolism

Substances

PIK3R1 protein, human
Class I Phosphatidylinositol 3-Kinases
Class Ia Phosphatidylinositol 3-Kinase
PIK3CD protein, human