GenomeLaser: fast and accurate haplotyping from pedigree genotypes

Bioinformatics. 2015 Dec 15;31(24):3984-7. doi: 10.1093/bioinformatics/btv452. Epub 2015 Aug 18.

Abstract

We present a software tool called GenomeLaser that determines the haplotypes of each person from unphased high-throughput genotypes in family pedigrees. This method features high accuracy, chromosome-range phasing distance, linear computing, flexible pedigree types and flexible genetic marker types.

Availability and implementation: http://www.4dgenome.com/software/genomelaser.html.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Female
  • Genetic Markers
  • Genotype
  • Genotyping Techniques / methods*
  • Haplotypes*
  • Humans
  • Male
  • Pedigree*
  • Software*

Substances

  • Genetic Markers