Synthesis and Consecutive Reactions of α-Azido Ketones: A Review

Sadia Faiz; Ameer Fawad Zahoor; Nasir Rasool; Muhammad Yousaf; Asim Mansha; Muhammad Zia-Ul-Haq; Hawa Z E Jaafar

doi:10.3390/molecules200814699

Synthesis and Consecutive Reactions of α-Azido Ketones: A Review

Molecules. 2015 Aug 13;20(8):14699-745. doi: 10.3390/molecules200814699.

Authors

Sadia Faiz¹, Ameer Fawad Zahoor², Nasir Rasool³, Muhammad Yousaf⁴, Asim Mansha⁵, Muhammad Zia-Ul-Haq⁶, Hawa Z E Jaafar⁷

Affiliations

¹ Department of Chemistry, Government College University Faisalabad, Faisalabad-38000, Pakistan. [email protected].
² Department of Chemistry, Government College University Faisalabad, Faisalabad-38000, Pakistan. [email protected].
³ Department of Chemistry, Government College University Faisalabad, Faisalabad-38000, Pakistan. [email protected].
⁴ Department of Chemistry, Government College University Faisalabad, Faisalabad-38000, Pakistan. [email protected].
⁵ Department of Chemistry, Government College University Faisalabad, Faisalabad-38000, Pakistan. [email protected].
⁶ Office of Research, Innovation and Commercialization, Lahore College for Women University, Lahore-54600, Pakistan. [email protected].
⁷ Department of Crop Science, Faculty of Agriculture, Universiti Putra Malaysia, Serdang-43400, Selangor, Malaysia. [email protected].

Abstract

This review paper covers the major synthetic approaches attempted towards the synthesis of α-azido ketones, as well as the synthetic applications/consecutive reactions of α-azido ketones.

Keywords: azides; click reactions; drugs; heterocycles; synthetic applications; α-azido ketones.

Publication types

Review

MeSH terms

Azides / chemical synthesis*
Azides / chemistry*
Ketones / chemical synthesis*
Ketones / chemistry*

Substances

Azides
Ketones