Congenital Parvovirus B19 Infection: Persistent Viremia and Red Blood Cell Aplasia

Open Forum Infect Dis. 2015 Apr 15;2(2):ofv049. doi: 10.1093/ofid/ofv049. eCollection 2015 Apr.

Abstract

We describe a case of fetal parvovirus B19 infection resulting in preterm birth and leading to hydrops fetalis requiring multiple in utero transfusions. The infant developed chronic postnatal anemia responsive to intravenous immunoglobulin therapy. Serum viral load decreased after immunoglobulin treatment but remained detectable for over 1 year.

Keywords: congenital; fetal; hydrops; parvovirus.