Predictive Factors of Atelectasis Following Endoscopic Resection

Dig Dis Sci. 2016 Jan;61(1):181-8. doi: 10.1007/s10620-015-3844-0. Epub 2015 Aug 20.

Abstract

Background and aim: Atelectasis is one of the pulmonary complications associated with anesthesia. Little is known about atelectasis following endoscopic procedures under deep sedation. This study evaluated the frequency, risk factors, and clinical course of atelectasis after endoscopic resection.

Methods: A total of 349 patients who underwent endoscopic resection of the upper gastrointestinal tract at a single academic tertiary referral center from March 2010 to October 2013 were enrolled. Baseline characteristics and clinical data were retrospectively reviewed from medical records. To identify atelectasis, we compared the chest radiography taken before and after the endoscopic procedure.

Results: Among the 349 patients, 68 (19.5 %) had newly developed atelectasis following endoscopic resection. In univariate logistic regression analysis, atelectasis correlated significantly with high body mass index, smoking, diabetes mellitus, procedure duration, size of lesion, and total amount of propofol. In multiple logistic regression analysis, body mass index, procedure duration, and total propofol amount were risk factors for atelectasis following endoscopic procedures. Of the 68 patients with atelectasis, nine patients developed fever, and six patients displayed pneumonic infiltration. The others had no symptoms related to atelectasis.

Conclusions: The incidence of radiographic atelectasis following endoscopic resection was nearly 20 %. Obesity, procedural time, and amount of propofol were the significant risk factors for atelectasis following endoscopic procedure. Most cases of the atelectasis resolved spontaneously with no sequelae.

Keywords: Atelectasis; Endoscopic resection; Sedation.

MeSH terms

  • Aged
  • Chi-Square Distribution
  • Comorbidity
  • Deep Sedation / adverse effects
  • Endoscopy, Gastrointestinal / adverse effects*
  • Female
  • Gastrointestinal Tract / surgery*
  • Humans
  • Hypnotics and Sedatives / adverse effects
  • Incidence
  • Logistic Models
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Obesity / epidemiology
  • Operative Time
  • Propofol / adverse effects
  • Pulmonary Atelectasis / diagnostic imaging
  • Pulmonary Atelectasis / epidemiology*
  • Radiography
  • Republic of Korea / epidemiology
  • Retrospective Studies
  • Risk Factors
  • Tertiary Care Centers
  • Time Factors
  • Treatment Outcome

Substances

  • Hypnotics and Sedatives
  • Propofol