Everolimus overexposure in a heart transplant patient receiving clarithromycin for the treatment of pneumonia

Transpl Infect Dis. 2015 Dec;17(6):926-8. doi: 10.1111/tid.12446. Epub 2015 Oct 28.

Authors

F Pea^{1

2}, P Cojutti^{1

2}, V Tursi³, U Livi³, M Baraldo^{1

2}

Affiliations

¹ Institute of Clinical Pharmacology, Azienda Ospedaliero-Universitaria Santa Maria della Misericordia, Udine, Italy.
² Department of Experimental and Clinical Medical Sciences, University of Udine, Udine, Italy.
³ Cardiothoracic Department, Azienda Ospedaliero-Universitaria Santa Maria della Misericordia, Udine, Italy.

PMID: 26296391
DOI: 10.1111/tid.12446

No abstract available

Keywords: clarithromycin; drug-drug interaction; everolimus; medication reconciliation.

Publication types

Case Reports
Letter

MeSH terms

Aged
Anti-Bacterial Agents / administration & dosage
Anti-Bacterial Agents / pharmacokinetics
Anti-Bacterial Agents / pharmacology
Clarithromycin / administration & dosage
Clarithromycin / pharmacokinetics*
Clarithromycin / pharmacology*
Drug Interactions
Everolimus / administration & dosage
Everolimus / blood
Everolimus / pharmacokinetics*
Everolimus / therapeutic use*
Female
Heart Transplantation / adverse effects*
Humans
Immunosuppressive Agents / administration & dosage
Immunosuppressive Agents / blood
Immunosuppressive Agents / pharmacokinetics
Immunosuppressive Agents / therapeutic use
Pneumonia, Bacterial / drug therapy*

Substances

Anti-Bacterial Agents
Immunosuppressive Agents
Everolimus
Clarithromycin