Front propagation speeds of T7 virus mutants

V L de Rioja; J Fort; N Isern

doi:10.1016/j.jtbi.2015.08.005

Front propagation speeds of T7 virus mutants

J Theor Biol. 2015 Nov 21:385:112-8. doi: 10.1016/j.jtbi.2015.08.005. Epub 2015 Aug 21.

Authors

V L de Rioja¹, J Fort², N Isern²

Affiliations

¹ Complex Systems Laboratory, Departament de Física, Universitat de Girona, 17071 Girona, Catalonia, Spain. Electronic address: [email protected].
² Complex Systems Laboratory, Departament de Física, Universitat de Girona, 17071 Girona, Catalonia, Spain.

PMID: 26300067
DOI: 10.1016/j.jtbi.2015.08.005

Abstract

We propose a new reaction-diffusion model with an eclipse time to study the spread of viruses on bacterial populations. This new model is both biologically and physically sound, unlike previous ones. We determine important parameter values from experimental data, such as the one-step growth. We verify the proposed model by comparing theoretical and experimental data of the front propagation speed for several T7 virus strains.

Keywords: Biophysics; Front propagation; Mathematical model; Reaction–diffusion equations; Virus dynamics.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Bacteriophage T7 / genetics
Bacteriophage T7 / physiology*
Diffusion
Escherichia coli / virology
Models, Biological*
Mutation
Virus Replication