Nickel-Cobalt Oxide Decorated Three-Dimensional Graphene as an Enzyme Mimic for Glucose and Calcium Detection

ACS Appl Mater Interfaces. 2015 Sep 30;7(38):21089-94. doi: 10.1021/acsami.5b06299. Epub 2015 Sep 15.

Abstract

Glucose and calcium ion play key roles in human bodies. The needlelike NiCo2O4 nanostructures are in situ deposited on three-dimensional graphene foam (3DGF) by a facile hydrothermal procedure. The structure and morphology of the hierarchical NiCo2O4/3DGF are characterized by scanning electron microscopy, transmission electron microscopy, and X-ray diffraction. With the self-standing NiCo2O4/3DGF as electrochemical electrode, it can realize the high-sensitivity detections for glucose and calcium ion. The limit of detection can reach 0.38 and 4.45 μM, respectively. In addition, the electrochemical electrode presents excellent selectivity for glucose and calcium ion. This study demonstrates that NiCo2O4/3DGF is a unique and promising material for practical application in both glucose and calcium ion sensing.

Keywords: 3D graphene; calcium ion; cobalt nickel oxide; glucose; sensitivity sensing.

MeSH terms

  • Biosensing Techniques
  • Calcium / analysis*
  • Cobalt / chemistry*
  • Electrochemistry
  • Electrodes
  • Glucose / analysis*
  • Graphite / chemistry*
  • Hydrogen Peroxide / chemistry
  • Ions
  • Nickel / chemistry*
  • Oxides / chemistry*
  • X-Ray Diffraction

Substances

  • Ions
  • Oxides
  • Cobalt
  • Graphite
  • Nickel
  • Hydrogen Peroxide
  • Glucose
  • Calcium
  • cobalt oxide