Schisandrosides A-D, Dibenzocyclooctadiene Lignan Glucosides from the Roots of Schisandra chinensis

Chem Pharm Bull (Tokyo). 2015;63(9):746-51. doi: 10.1248/cpb.c15-00400.

Abstract

Four new dibenzocyclooctadiene lignan glucosides, schisandrosides A-D (1-4), as well as two known rare nortriterpenoids, micrandilactone C (5) and propindilactone Q (6), were isolated from the roots of Schisandra chinensis BAILLON (Schisandraceae). The structure of compounds 1-4 were elucidated by physical and spectroscopic data interpretation. To the best of our knowledge, schisandrosides A-D (1-4) represent the first example of a dibenzocyclooctadiene lignan glycoside.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cyclooctanes / chemistry*
  • Cyclooctanes / isolation & purification
  • Glucosides / chemistry*
  • Glucosides / isolation & purification
  • Lignans / chemistry*
  • Lignans / isolation & purification
  • Molecular Conformation
  • Plant Extracts / chemistry*
  • Plant Extracts / isolation & purification
  • Plant Roots / chemistry*
  • Schisandraceae / chemistry*
  • Stereoisomerism

Substances

  • Cyclooctanes
  • Glucosides
  • Lignans
  • Plant Extracts
  • dibenzocyclooctadiene lignan